Antagonistic Hormone Pairs

Question

Which of the following pair of hormones act antagonistic to each other-

Select an answer

Which of the following pair of hormones act antagonistic to each other-

  1. Calcitonin & PTH
  2. Aldosterone & Atrial natriuretic peptide (ANP)
  3. Insulin & Glucagon
  4. All the above — Correct Answer
Explanation:
Correct Answer: All the above

All three pairs are classic antagonistic hormone pairs that together maintain homeostasis.

Antagonistic Pairs Explained
  • Calcitonin (thyroid C-cells) vs. PTH (parathyroid glands):
    • Calcitonin → ↓ blood Ca²⁺ (promotes Ca²⁺ deposition in bone, inhibits osteoclasts)
    • PTH → ↑ blood Ca²⁺ (increases renal Ca²⁺ reabsorption, activates osteoclasts, stimulates Vitamin D activation)
  • Aldosterone (adrenal cortex) vs. ANP (cardiac atria):
    • Aldosterone → ↑ Na⁺ reabsorption → ↑ blood volume/pressure
    • ANP → ↑ Na⁺ secretion → ↓ blood volume/pressure
  • Insulin (β-cells of islets) vs. Glucagon (α-cells of islets):
    • Insulin → ↓ blood glucose (promotes glucose entry into cells)
    • Glucagon → ↑ blood glucose (glycogenolysis + gluconeogenesis in liver)
    • Somatostatin (δ-cells) inhibits both insulin and glucagon — it modulates, not opposes one

📚 About this Topic — Animal Physiology

This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.

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