Effect Similar to PMSG

The effect of PMSG (Pregnant Mare Serum Gonadotropin) is similar to:

Correct Answer: FSH

PMSG (Pregnant Mare Serum Gonadotropin), also known as eCG (Equine Chorionic Gonadotropin), has a biological effect predominantly similar to FSH (Follicle Stimulating Hormone). It promotes follicular development and is widely used for superovulation protocols in cattle and sheep.

Comparison: PMSG vs. hCG

• PMSG (eCG): FSH-like effect → follicle growth and superovulation
• hCG (Human Chorionic Gonadotropin): LH-like effect → ovulation induction

Half-life Comparison

• PMSG has the longest half-life of all gonadotropins (~6 days), due to its very high sialic acid content.
• Half-life order: PMSG > hCG > FSH > LH > Oxytocin

Use in Superovulation

PMSG + hCG combination is used in embryo transfer programs: PMSG stimulates multiple follicle development (FSH action), then hCG triggers their ovulation (LH action).