Glucose Tolerance Factor — Mineral Involved

Correct Answer: Chromium (Cr)

Chromium (Cr) is known as the 'Glucose Tolerance Factor (GTF)'. It potentiates the action of insulin and improves glucose uptake by cells.

Chromium Deficiency

Chromium deficiency causes 'Impaired glucose tolerance' — the body cannot utilise glucose effectively, resembling a diabetic state. This is the condition described in Question 200 of the book.

Chromium Facts

• Form: Trivalent Cr³⁺ is biologically active; hexavalent Cr⁶⁺ is toxic
• GTF is a complex of Cr³⁺ with nicotinic acid, glycine, glutamic acid, and cysteine
• Important in insulin signalling and carbohydrate metabolism

Other 'Factor' Names in Nutrition

• Glucose Tolerance Factor → Chromium (Cr)
• Anti-infective vitamin → Vitamin A
• Anti-sterility vitamin → Vitamin E
• Anti-stress vitamin → Vitamin C
• Anti-haemorrhagic factor → Vitamin K