Match: Immunology Concepts

Question

Match the column:

TABLE-I TABLE-II
1) Bone marrow a) Secretory antibody
2) Spleen b) Cross the placenta
3) IgG c) Active immunity
4) IgA d) Passive immunity
5) Vaccination e) Secondary lymphoid organ
6) Colostrum f) Primary lymphoid organ
Select an answer
View Complete Answer & Explanation

Question (English)

Match the column:

TABLE-I TABLE-II
1) Bone marrow a) Secretory antibody
2) Spleen b) Cross the placenta
3) IgG c) Active immunity
4) IgA d) Passive immunity
5) Vaccination e) Secondary lymphoid organ
6) Colostrum f) Primary lymphoid organ
  1. 1-f, 2-e, 3-b, 4-a, 5-c, 6-d ✓ Correct
  2. 1-e, 2-f, 3-b, 4-a, 5-c, 6-d
  3. 1-f, 2-e, 3-a, 4-b, 5-c, 6-d
  4. 1-f, 2-e, 3-b, 4-a, 5-d, 6-c
Explanation:
Correct Answer: 1-f, 2-e, 3-b, 4-a, 5-c, 6-d
Explanation of Each Match
  • 1-f) Bone marrow → Primary lymphoid organ: Bone marrow is where B-lymphocytes and all blood cells originate and mature. It is a primary lymphoid organ (also includes thymus and bursa of Fabricius in birds).
  • 2-e) Spleen → Secondary lymphoid organ: The spleen is a secondary lymphoid organ where mature lymphocytes encounter and respond to antigens. Other secondary lymphoid organs: lymph nodes, tonsils, Peyer's patches.
  • 3-b) IgG → Crosses the placenta: IgG is the only immunoglobulin that can cross the placenta (via FcRn receptors on placental cells), providing natural passive immunity to the newborn. It is also the most abundant (80% of total Ig).
  • 4-a) IgA → Secretory antibody: IgA is found in secretions (tears, saliva, sweat, colostrum, intestinal juice, mucus) and is therefore called the 'secretory antibody.' It protects mucosal surfaces.
  • 5-c) Vaccination → Active immunity: Vaccination stimulates the body's own immune cells to produce antibodies = Artificial active immunity. The body becomes actively involved in producing its own defense.
  • 6-d) Colostrum → Passive immunity: Colostrum (first milk) contains maternal IgG and IgA. When consumed by neonates, they receive ready-made antibodies = Natural passive immunity.
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