Topics:
Animal Physiology, Animal Refresher
Match the Column – Hemoglobin Derivatives
Match the column:
| TABLE-I | TABLE-II |
|---|---|
| 1) Oxyhemoglobin | a) Hb (Fe³⁺) |
| 2) Carbaminohemoglobin | b) Hb+CO |
| 3) Carboxyhemoglobin | c) Hb+CO₂ |
| 4) Methemoglobin | d) Hb+O₂ |
- 1-d, 2-c, 3-b, 4-a — Correct Answer
- 1-c, 2-d, 3-b, 4-a
- 1-d, 2-b, 3-c, 4-a
- 1-a, 2-c, 3-b, 4-d
Explanation:
Correct Answer: 1-d, 2-c, 3-b, 4-a
Each hemoglobin derivative is formed by the binding of hemoglobin with a specific ligand:
- 1-d: Oxyhemoglobin = Hb + O₂ — Formed in the lungs where oxygen is abundant. Fe²⁺ binds reversibly to O₂. Bright red colour of arterial blood. Carries ~98.5% of blood oxygen. Normal and reversible binding.
- 2-c: Carbaminohemoglobin = Hb + CO₂ — Formed when CO₂ binds to amino groups of the globin chains (not to the heme). Carries ~23% of CO₂ in blood. Formed in tissues where CO₂ is produced.
- 3-b: Carboxyhemoglobin = Hb + CO — Carbon Monoxide (CO) binds to Fe²⁺ with 250 times higher affinity than O₂. Cherry-red colour of blood. Highly toxic — prevents O₂ binding and shifts O₂ dissociation curve left. Example: CO poisoning in animals housed in poorly ventilated sheds with combustion heaters.
- 4-a: Methemoglobin = Hb (Fe³⁺) — Formed when Fe²⁺ in hemoglobin is oxidized to Fe³⁺ (cannot bind O₂). Chocolate-brown coloured blood. Seen in nitrate/nitrite poisoning in cattle. Treated with Methylene Blue.
📚 About this Topic — Animal Physiology
This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.
