Topics:
Animal Refresher, Animal Reproduction
Effect Similar to hCG
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Question (English)
The effect of hCG (Human Chorionic Gonadotropin) is similar to:
- LH ✓ Correct
- FSH
- PGF₂α
- Progesterone
Explanation:
Correct Answer: LH
hCG (Human Chorionic Gonadotropin) has an effect predominantly similar to LH (Luteinizing Hormone). It binds to LH receptors and triggers ovulation of mature follicles and luteinization of granulosa cells.
Clinical Uses of hCG
- Ovulation induction: hCG is injected to trigger ovulation of a dominant follicle in embryo transfer and timed AI programs.
- Treatment of cystic ovarian disease (COD): especially follicular cysts in cattle.
- Treatment of subestrus/silent heat in cattle.
Comparison: PMSG vs. hCG
- PMSG: FSH-like → follicle stimulation/superovulation
- hCG: LH-like → ovulation trigger, luteinization
Half-life of hCG
hCG has a half-life of about 11 hours, which is longer than LH (~60 minutes) but shorter than PMSG (~6 days).
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