Topics:
Animal Physiology, Animal Refresher
Site of Krebs Cycle and Beta-Oxidation
The main site of Kreb's cycle & β-oxidation of fatty acid is-
- Cytoplasm
- Mitochondria — Correct Answer
- Endoplasmic reticulum
- Golgi bodies
Explanation:
Correct Answer: Mitochondria
Both the Krebs cycle (TCA/Citric acid cycle) and β-oxidation of fatty acids occur in the mitochondria — hence it is called the 'powerhouse of the cell.'
Metabolic Pathway Locations
- Mitochondria: Krebs cycle, β-oxidation of fatty acids, Oxidative phosphorylation (ETC), Pyruvate oxidation
- Cytoplasm (Cytosol): Glycolysis, Fatty acid synthesis (lipogenesis), HMP shunt
- Both: Gluconeogenesis (some steps in mitochondria, some in cytosol)
- Ribosome: Protein synthesis (translation)
- Golgi body: Transport and packaging of proteins
- Lysosome: Intracellular digestion ('suicide bag')
Krebs Cycle Key Facts
- Also known as: TCA (Tricarboxylic acid) / Citric acid cycle
- It is an amphibolic pathway — both catabolic and anabolic
- One turn produces: 3 NADH + 1 FADH₂ + 1 GTP + 2 CO₂
- Complete oxidation of 1 glucose → 36–38 ATP molecules
📚 About this Topic — Animal Physiology
This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.