Topics:
Animal Physiology, Animal Refresher
General Factors Required for RBC Formation
General factors required for RBC formation include:
- All the above — Correct Answer
- Erythropoietin only
- Haemopoietin growth factor only
- Thyroxin only
Explanation:
Correct Answer: All the above
RBC formation (erythropoiesis) requires multiple general growth-stimulating factors working together:
General Factors for RBC Formation
- Erythropoietin: The principal erythroid growth factor, secreted by kidney in response to hypoxia; directly stimulates erythroid precursor proliferation.
- Haemopoietin growth factors: A broad category of growth factors (including colony-stimulating factors) that promote the survival and proliferation of haematopoietic stem cells.
- Thyroxin: Thyroid hormone that increases basal metabolic rate, stimulates oxygen demand, and thereby indirectly promotes erythropoiesis.
Maturation Factors (Different from General Growth Factors)
- Vitamin B12 (extrinsic Castle factor)
- Folic acid
- Intrinsic Castle factor (secreted by parietal cells of stomach)
These maturation factors are required for proper DNA synthesis and nuclear maturation of developing RBCs, whereas general factors are required for the overall stimulation and proliferation of erythroid cells.
📚 About this Topic — Animal Physiology
This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.
