Topics:
Animal Physiology, Animal Refresher
Normal GFR Value in Humans
Normal value of glomerular filtration rate (GFR) in human is:
- 125 ml/min — Correct Answer
- 150 ml/min
- 175 ml/min
- 200 ml/min
Explanation:
Correct Answer: 125 ml/min
The normal Glomerular Filtration Rate (GFR) in humans is 125 ml/min, which equals approximately 180 litres/day. This is the volume of plasma filtered by all nephrons of both kidneys per unit time.
GFR Key Facts
- Normal GFR: 125 ml/min or 180 L/day in humans.
- Of the 180 L filtered per day, only ~1.8 L (1%) is excreted as urine; the rest is reabsorbed.
- GFR is measured clinically by creatinine clearance (endogenous) or inulin clearance (exogenous gold standard).
- High plasma creatinine = decreased GFR = kidney disease.
GFR Measurement Methods
| Substance | Property | Measures |
|---|---|---|
| Inulin | Freely filtered; not secreted or reabsorbed | True GFR (gold standard) |
| Creatinine | Endogenous; freely filtered; small tubular secretion | Approximate GFR (clinical use) |
| PAH (para-aminohippuric acid) | Filtered + secreted; 100% extracted | Renal plasma flow (RPF) |
📚 About this Topic — Animal Physiology
This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.
