Oxygen Molecules Carried per Hemoglobin Molecule

Question

Number of oxygen molecules carried by each hemoglobin (Hb) molecule is:

Select an answer

Number of oxygen molecules carried by each hemoglobin (Hb) molecule is:

  1. 2
  2. 4 — Correct Answer
  3. 6
  4. 8
Explanation:
Correct Answer: 4

Each hemoglobin molecule carries 4 molecules of oxygen — one per heme group (one per iron atom).

Hemoglobin Structure
  • One Hb molecule = 4 polypeptide chains (2α + 2β) + 4 heme groups
  • Each heme group = 1 iron atom (Fe²⁺) + porphyrin ring
  • Each Fe²⁺ binds 1 O₂ → total 4 O₂ per Hb molecule
Cooperative Binding

Hemoglobin shows cooperative binding — binding of the first O₂ increases affinity for the next O₂ molecule, producing the characteristic sigmoidal (S-shaped) oxygen-hemoglobin dissociation curve.

Key Numbers
  • 1 Hb molecule → 4 O₂
  • 1 gram Hb → 1.34 ml O₂
  • 15 g/dl Hb (normal) → ~20 ml O₂ per 100 ml blood

📚 About this Topic — Animal Physiology

This multiple choice question is from Animal Physiology, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Physiology to strengthen your preparation.

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