Gene Frequency Calculation in Multiple Allelic System

Question

In a multiple allelic system with 3 alleles (A₁, A₂, A₃), if frequency of A₁ = 0.25 and frequency of A₂ = 0.35, what is the frequency of A₃?

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In a multiple allelic system with 3 alleles (A₁, A₂, A₃), if frequency of A₁ = 0.25 and frequency of A₂ = 0.35, what is the frequency of A₃?

  1. 0.25
  2. 0.35
  3. 0.10
  4. 0.40 — Correct Answer
Explanation:
Correct Answer: 0.40

The sum of frequencies of all alleles at one locus must equal 1.
A₁ + A₂ + A₃ = 1
0.25 + 0.35 + A₃ = 1
A₃ = 1 − 0.60 = 0.40

Multiple Allelism — Key Facts
  • More than two alternative forms of a gene located on the same locus of homologous chromosomes.
  • Multiple alleles are produced by mutation.
  • Found in the population, not in a single individual.
  • No. of possible genotypes = N(N+1)/2, where N = no. of alleles.
Examples
  • ABO blood group in human: 3 alleles (Iᴬ, Iᴮ, Iᴼ)
  • Coat colour in Rabbit: 4 alleles
  • Eye colour in Drosophila: 15 alleles

📚 About this Topic — Animal Genetics & Breeding

This multiple choice question is from Animal Genetics & Breeding, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Genetics & Breeding to strengthen your preparation.

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