Mechanism of VFA Absorption

Question

The absorption of VFA occurs in ruminant by:

Select an answer

The absorption of VFA occurs in ruminant by:

  1. Active transport
  2. Passive diffusion — Correct Answer
  3. Facilitated transport
  4. None
Explanation:
Correct Answer: Passive diffusion

VFA (Volatile Fatty Acids) are absorbed across the rumen wall by passive diffusion — no energy (ATP) is required. The concentration gradient drives movement of undissociated (protonated) VFA molecules from the high-concentration rumen lumen across the lipid bilayer of rumen epithelial cells into portal blood.

Absorption Mechanisms in the GIT
Substance Absorption Mechanism Site
VFAs (in ruminants) Passive diffusion Rumen wall (papillae)
Glucose (in non-ruminants) Active transport (Na⁺-dependent) Small intestine
Amino acids Active transport Ileum (ruminants); Duodenum/jejunum (non-ruminants)
Fatty acids (long-chain) Passive diffusion (as micelles) Proximal jejunum
Factors Affecting VFA Absorption Rate
  • Rumen pH → lower pH → more undissociated VFA → faster passive diffusion.
  • Chain length → Butyrate > Propionate > Acetate (lipid solubility increases with chain length).
  • Surface area → rumen papillae size and density determine absorption capacity.
Why Other Options Are Wrong
  • Active transport → requires ATP and carrier proteins; VFA absorption across rumen wall does not require energy input.
  • Facilitated transport → uses carrier proteins but no ATP; not the established mechanism for ruminal VFA absorption.
  • None → passive diffusion is the correct and well-established mechanism.

📚 About this Topic — Animal Nutrition

This multiple choice question is from Animal Nutrition, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Nutrition to strengthen your preparation.

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