Absorption Rate of Volatile Fatty Acids

Question

Rate of VFA absorption across the rumen wall follows the order:

Select an answer

Rate of VFA absorption across the rumen wall follows the order:

  1. Butyrate > Propionate > Acetate — Correct Answer
  2. Propionate > Acetate > Butyrate
  3. Acetate > Propionate > Butyrate
  4. None
Explanation:
Correct Answer: Butyrate > Propionate > Acetate

The rate of VFA absorption across the rumen wall follows the order: Butyrate > Propionate > Acetate. This is because absorption rate is related to the lipid solubility and chain length of the VFA — longer chain and more lipophilic acids (butyrate) diffuse faster across the epithelial membrane.

VFA Absorption Characteristics
VFA Chain Length Absorption Rate Rumen Proportion
Butyrate (C4) 4 carbons Fastest ✓ ~10%
Propionate (C3) 3 carbons Intermediate ~20%
Acetate (C2) 2 carbons Slowest ~65%
Mechanism of VFA Absorption
  • VFAs are absorbed by passive diffusion — no energy expenditure required.
  • Undissociated (protonated) form of VFA diffuses more readily → favoured at lower rumen pH.
  • The rumen papillae provide the large surface area needed for rapid VFA absorption.
  • Butyrate is rapidly converted to β-hydroxybutyrate within the rumen epithelial cells themselves before entering portal blood.
Why Other Options Are Wrong
  • Propionate > Acetate > Butyrate → incorrect order; butyrate, not propionate, is fastest.
  • Acetate > Propionate > Butyrate → completely reversed; acetate (most abundant but smallest) is absorbed most slowly.
  • None → Butyrate > Propionate > Acetate is the established order.

📚 About this Topic — Animal Nutrition

This multiple choice question is from Animal Nutrition, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Nutrition to strengthen your preparation.

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