Definition of EC50
EC50 is defined as:
- LD50
- EC50 (agonist) — Correct Answer
- Antagonist IC50
- ED50
Explanation:
Correct Answer: Concentration of agonist producing half maximal effect
EC50 is the concentration of an agonist that produces half maximal effect. It is a measure of potency — a lower EC50 means a more potent drug (less drug needed to achieve half-maximal response).
Related Terms
- IC50: Concentration of an antagonist that produces half maximal inhibition.
- ED50: Dose producing desired effect in 50% of a population.
- LD50: Dose producing death in 50% of a population.
- Therapeutic Index: LD50 / ED50 — a measure of drug safety margin.
📚 About this Topic — Veterinary Pharmacology and Toxicology
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