Intrinsic Activity of a Full Agonist
Intrinsic activity of a full agonist is:
- 1 — Correct Answer
- 0.5
- >1
Explanation:
Correct Answer: 1
A full agonist has an intrinsic activity of 1. It can produce a maximal response by occupying all or just a fraction of receptors.
Intrinsic Activity Values
- Full agonist: Intrinsic activity = 1 (maximal response).
- Partial agonist: Intrinsic activity between 0 and 1 (submaximal response even when all receptors occupied).
- Pure antagonist: Intrinsic activity = 0 (no response, only blocks access of agonist).
- Inverse agonist: Produces effects opposite to agonists.
Additional Definitions
- Affinity: Capacity of a drug to bind to a receptor.
- Potency: Concentration range over which increasing responses are produced.
- Efficacy: Maximum effect produced by a drug — the peak of the dose-response curve.
📚 About this Topic — Veterinary Pharmacology and Toxicology
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