Identification of Goitrogenic Agents

Question

Which of the following is a "Goitrogenic agent"?

Select an answer

Which of the following is a "Goitrogenic agent"?

  1. Gossypol
  2. Glucosinolate — Correct Answer
  3. Mimosine
  4. All
Explanation:
Correct Answer: Glucosinolate

Glucosinolates are the classic goitrogenic agents. Found in plants of the Brassicaceae family (mustard, rapeseed, cabbage, cauliflower, turnip), they are hydrolyzed to goitrin (5-vinyloxazolidine-2-thione) and isothiocyanates, which interfere with iodine uptake by the thyroid gland, causing goitre.

Goitrogenic Agents — Classification
Agent Source Mechanism
Glucosinolate → Goitrin Brassica plants (mustard, rapeseed) Blocks iodine organification in thyroid
Cyanide (HCN) Not goitrogenic (causes different toxicity)
Anti-Nutritional Factors — Quick Reference
Anti-Nutritional Factor Plant Treatment
Glucosinolate (goitrogen) Brassica family plants Iodine supplement
Gossypol Cotton seed cake FeSO₄ / Iron supplement
Mimosine Subabool (Leucaena) FeSO₄ / Iron supplement
Saponin Lucerne (Alfalfa) Mineral oil / Simethicone (Bloatosil)
Tannin Babul seeds, Khejri
Why Other Options Are Wrong
  • Gossypol → cardiotoxic and reproductive toxin from cottonseed; not a goitrogen.
  • Mimosine → from Subabool/Leucaena; causes hair loss and oesophageal lesions; not a goitrogen.
  • All → only glucosinolate causes goitre; gossypol and mimosine have different toxicity mechanisms.

📚 About this Topic — Animal Nutrition

This multiple choice question is from Animal Nutrition, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Nutrition to strengthen your preparation.

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