Primary Cause of Genetic Variation

Question

Biggest cause of genetic variation-

Select an answer

Biggest cause of genetic variation-

  1. Segregation — Correct Answer
  2. Crossing over
  3. Selection
  4. None
Explanation:
Correct Answer: Segregation

Segregation (Mendel's First Law — Law of Purity of Gametes) is the biggest ongoing cause of genetic variation. Every meiotic division reshuffles alleles into new combinations, continuously generating genetic diversity in offspring every generation.

Causes of Genetic Variation — Ranking
Rank Cause Mechanism
1st (Biggest) Segregation Alleles separate into gametes during meiosis → billions of new genotypic combinations possible in each generation
2nd Crossing over Exchange of segments between homologous chromosomes at Pachytene stage → new allelic combinations on chromosomes
3rd Mutation Ultimate source of ALL new alleles; but rate is very slow (10⁻⁵ to 10⁻⁶ per locus per generation)
Others Migration, Selection, Genetic drift Alter frequencies of existing variation rather than creating new alleles

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This multiple choice question is from Animal Genetics & Breeding, Animal Refresher. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Animal Genetics & Breeding to strengthen your preparation.

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