Second Messenger for α1 Adrenoceptors and H1 Receptors
Which second messenger serves for α1 adrenoceptors and H1 receptors?
- cAMP
- cGMP
- Ca²⁺ only
- IP3 and DAG — Correct Answer
Explanation:
Correct Answer: IP3 and DAG
IP3 (Inositol triphosphate) and DAG (Diacylglycerol) serve as second messengers for α1 adrenoceptors, H1 receptors, and cholecystokinin. They are degradation products of membrane phospholipid by the enzyme phospholipase C.
Second Messengers for Key Receptors
- cAMP: Adenosine, opioid, VIP, α2 and β adrenoceptors, H2 receptors.
- cGMP: Angiotensin receptor.
- IP3 and DAG: α1 adrenoceptors, H1 receptors, cholecystokinin.
General Rule
cAMP is generally stimulatory while cGMP is generally inhibitory in nature when both are present in the same cell.
📚 About this Topic — Veterinary Pharmacology and Toxicology
This multiple choice question is from Veterinary Pharmacology and Toxicology, Veterinary Science. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Veterinary Pharmacology and Toxicology to strengthen your preparation.
