Alternative Name for Competitive Antagonism
Competitive antagonism is also called:
- Unsurmountable antagonism
- Surmountable antagonism — Correct Answer
- Physiological antagonism
- Chemical antagonism
Correct Answer: Surmountable antagonism
Competitive antagonism is also called surmountable antagonism because the antagonistic effect can be overcome by increasing the concentration of the agonist. The antagonist competes for the same binding site as the agonist.
Example: Acetylcholine and its antagonist atropine.
Contrast: Non-Competitive Antagonism
Non-competitive antagonism is also called unsurmountable antagonism — the antagonist binds to a different (allosteric) site and the effect cannot be overcome by increasing agonist concentration.
Example: Acetylcholine and decamethonium.
📚 About this Topic — Veterinary Pharmacology and Toxicology
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