Contraindication of Magnesium Sulfate as Purgative
Magnesium sulfate used as an osmotic purgative is contraindicated in:
- Constipation
- Congestive heart failure
- Hepatic encephalopathy
- Renal insufficiency — Correct Answer
Correct Answer: Renal insufficiency
Magnesium salts are contraindicated in renal insufficiency — because if magnesium ions are absorbed and cannot be excreted efficiently by the kidneys, they accumulate and cause magnesium toxicity (neuromuscular depression, cardiac effects).
Sodium Purgative Salts Contraindication
Sodium salts (sodium sulfate, sodium phosphate) should not be used in patients with Congestive Heart Failure (CHF) and other sodium-retaining states — to avoid sodium and water retention and worsening fluid overload.
Other Notes on Osmotic Purgatives
- Cathartics of choice for elimination of poisons.
- Sodium phosphate and sodium tartrate given rectally to dogs; NOT to cats (cause hyperphosphatemia).
- Repeated use can cause fluid and electrolyte imbalance.
📚 About this Topic — Veterinary Pharmacology and Toxicology
This multiple choice question is from Veterinary Pharmacology and Toxicology, Veterinary Science. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Veterinary Pharmacology and Toxicology to strengthen your preparation.
