Number of Subjects in Phase 1 Clinical Trial
In Phase 1 clinical trials, how many healthy volunteers are typically enrolled?
- 25–50 — Correct Answer
- 100–200
- 500–1000
- >1000
Explanation:
Correct Answer: 25–50
Phase 1 clinical trials involve a small number — 25–50 healthy volunteers — to establish dosage effects and probable limits of safe clinical dosage range.
Phases of Clinical Trials
- Phase 1: 25–50 healthy volunteers; open (non-blind); determines safe dose range; pharmacokinetics measured.
- Phase 2: 100–200 patients with target disease; single-blind; evaluates efficacy.
- Phase 3: Thousands of patients; double-blind, crossover; confirms safety and efficacy.
- Phase 4: Post-marketing surveillance; no fixed duration; monitors for rare adverse effects in real-world conditions.
📚 About this Topic — Veterinary Pharmacology and Toxicology
This multiple choice question is from Veterinary Pharmacology and Toxicology, Veterinary Science. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Veterinary Pharmacology and Toxicology to strengthen your preparation.
