GI Pharmacology Drug-Mechanism Match
Match the column:
| TABLE-I (Drug) | TABLE-II (Mechanism/Use) |
|---|---|
| 1. Apomorphine | (a) 5HT3 antagonist |
| 2. Ondansetron | (b) D2 agonist emetic |
| 3. Metoclopramide | (c) Proton pump inhibitor |
| 4. Omeprazole | (d) D2 antagonist/prokinetic |
| 5. Sucralfate | (e) Gastric protectant, acidic |
- 1-b, 2-a, 3-d, 4-c, 5-e — Correct Answer
- 1-a, 2-b, 3-d, 4-c, 5-e
- 1-b, 2-a, 3-c, 4-d, 5-e
- 1-b, 2-d, 3-a, 4-c, 5-e
Explanation:
Correct Answer: 1-b, 2-a, 3-d, 4-c, 5-e
- Apomorphine (1-b): D2 agonist emetic that acts on CTZ; contraindicated in cats (causes excitement).
- Ondansetron (2-a): 5HT3 antagonist; potent antiemetic especially for cancer chemotherapy.
- Metoclopramide (3-d): D2 antagonist + weak 5HT3 antagonist; also a prokinetic that increases upper GI motility and facilitates gastric emptying.
- Omeprazole (4-c): Proton pump inhibitor; irreversibly inhibits K⁺H⁺-ATPase; must be given as enteric-coated preparation.
- Sucralfate (5-e): Gastric band aid (complex of sulfated sucrose and aluminum hydroxide); polymerizes at pH <4 and adheres to ulcer base.
📚 About this Topic — Veterinary Pharmacology and Toxicology
This multiple choice question is from Veterinary Pharmacology and Toxicology, Veterinary Science. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Veterinary Pharmacology and Toxicology to strengthen your preparation.
