Types of Adverse Drug Effects Match
Match the column:
| TABLE-I (Adverse Effect) | TABLE-II (Example) |
|---|---|
| 1. Side effect | (a) Paracetamol liver damage |
| 2. Toxic effect | (b) Barbiturate excitement |
| 3. Idiosyncrasy | (c) Atropine dry mouth |
| 4. Teratogenicity | (d) TB flare corticosteroids |
| 5. Secondary effect | (e) Thalidomide fetal defects |
- 1-a, 2-c, 3-b, 4-e, 5-d
- 1-c, 2-a, 3-b, 4-e, 5-d — Correct Answer
- 1-c, 2-b, 3-a, 4-e, 5-d
- 1-c, 2-a, 3-e, 4-b, 5-d
Explanation:
Correct Answer: 1-c, 2-a, 3-b, 4-e, 5-d
- Side effect (1-c): Expected and unavoidable effect — dryness of mouth with atropine treatment.
- Toxic effect (2-a): Due to overdosage — paracetamol-induced liver damage, coma by barbiturates.
- Idiosyncrasy (3-b): Genetically determined abnormal reactivity — barbiturate-induced excitement and confusion in some patients.
- Teratogenicity (4-e): Ability to cause fetal abnormalities — thalidomide, anticancer drugs, tetracyclines.
- Secondary effect (5-d): Indirect consequence of primary effect — weakening of host immunity by corticosteroids leading to TB flare-up.
Other Key Adverse Effect Types
- Intolerance: Toxic effects at therapeutic doses in some individuals.
- Drug allergy: Immunologically mediated (hypersensitivity); needs priming dose.
- Photosensitivity: e.g. phenothiazine, sulfonamide, griseofulvin.
📚 About this Topic — Veterinary Pharmacology and Toxicology
This multiple choice question is from Veterinary Pharmacology and Toxicology, Veterinary Science. It has 4 options with a detailed explanation of the correct answer. Practice more MCQs from Veterinary Pharmacology and Toxicology to strengthen your preparation.